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Nature Immunology?????????????????????·???
????? ???????? ????????? zhangli ?????????: ?????: ??????? 2020-01-02  ???????1772
??????????????????????????????????л??????о??????Nature Immunology????????????T cells instruct myeloid cells to produce inflammasome-independent IL-1?? and cause autoimmunity???????????С???з???????????????T???????????????????????????????????????????????????1?????????????????????????????????
???? ???????????-1???interleukin-1???IL-1?????????????????????????????????IL-1?????????????????????????????????С???????У????в????????????????????T????????????????????????IL-1????????
???? ?о??????????IL-1???????????С?????????????????????Ч?CD4+ T????????????????mononuclear phagocytes??MPs?????????????????????CD4+ T????????????????TNF??tumor necrosis factor?????????????????MP???TNF???壨TNFR??????????IL-1??????ɡ?MP???????????????????Fas??CD4+ T????????Fas???壨FasL?????????°??????8??caspase-8????????IL-1???????С??????IL-1???????????????TNFR??Fas???????????????С??????CD4+ T??????????????????TNFR?CFas?Ccaspase-8??????????IL-1???????????CD4+ T??????????????????????е?????????????????????????Nature Immunology, Published: 17 Dec 2019??

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